During an asthma attack, muscles around the airways tighten up, making the airways narrower so less air flows through. Inflammation increases, and the airways become more swollen and even narrower Cells in the airways may also make more mucus than usual. This extra mucus also narrows the airways. These changes make it harder to breathe. When the airways react, they get narrower, and less air flows through to your lung tissue. Persistent symptoms include: