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Journals and Articles featuring BCV

Dr. Zamir Hayek set out to design the ideal multifunction ventilator that would be a clinical tool to assist nearly anyone.

He achieved this with the Hayek BCV,  and in doing so, birthed a new and powerful pulmonary treatment concept, Biphasic Cuirass Ventilation (BCV). BCV was a revolutionary treatment, facilitating patients respiratory support needs, without the side effects of PPV, or a facial mask interface. Coupled with its HFCWO and cough options to deliver multifunction respiratory support, BCV is the only non-invasive ventilation tool to support the work of breathing in a physiologically way. 

  1. Hayek Z, Ryan A, Eyal F, Jones R, Armengol J, King EG, Finer N. Comparison of High-Frequency Chest Wall compression with Conventional Mechanical Ventilation in Cats. Crit Care Med, 1987, 15L 676-681.
  2. Eyal F, Hayek Z, Armengol J, Jones R. High Frequency Chest Wall Compression in Cats with Normal Lungs. Pediatric Research, 1987, 21: 183-187
  3. Eyal F, Hayek Z, Armengol J, Jones R. Comparison of High-Frequency Negative-Pressure Oscillation with Conventional Mechanical Ventilation in Normal and Saline Lavaged Cats. Crit Care Med, 1986, 14: 724-729
  4. Hayek Z, Peliowski A, Ryan CA, Jones R, Finer N. External High Frequency Oscillation in Cats. Experience in the Normal Lung and After Saline Lung Lavage. Am Rev Respir Dis, 1986; 133: 630-634,
  5. Barrington K, Ryan CA, Peliowski A, Nosko M, Finer N. The Effects of Negative Pressure External High Frequency Oscillation on Cerebral Blood Flow and Cardiac Output of the Monkey. Pediatric Res. 1987, 21: 166-169
  6. Hayek Z, Peliowski A, Ryan CA, Jones R, Finer N. External High Frequency Oscillation in Cats: Experience in the Normal Lung and After Salilne Lavage. 1987, The Year Book of Critical Care Medicine, pp 199-201.
  7. Hayek Z, Sohar E. External High Frequency Oscillation – Concept and Practice. Intensive Care World, 1993, 10: 36 – 40
  8. Hayek Z, Schonfeld T. External High Frequency Oscillation Around Negative Baseline – Preliminary Trial in Humans. Proceedings 5th Congress on Intensive and Critical Care Medicine, Kyoto, Japan, September 3-8, 1989, Excerpta Medica, 1990, p.761-762
  9. Petros AJ, Fernando SSD, Shenoy VS, Al-Saady NM. The Hayek Oscillator – Nomograms for Tidal Volume and Minute Ventilation using External High Frequency Oscillation. Anaesthesia July 1995, 50 (7): 601-606
  10. Penny D, Hayek Z, Redington A. The Effects of Positive and Negative Extrathoracic Pressure Ventilation on Pulmonary Blood Flow after Total Cavolpulmonary Shunt Procedure. Internat. Jnl of Cardiology, 30 (1991) 128-130.
  11. Penny DJ, Hayek Z, Rawle P, Rigby ML, Redington AN. Ventilation with External High Frequency Oscillation around a Negative Baseline Increases Pulmonary Blood Flow after the Fontan Operation. Cardiol Young 1992, 2: 277-280
  12. Shekerdemian L.S., Shore D.F., Lincoln C., Bush A. and Redington A.N. Negative-pressure Ventilation Improves Cardiac Output after Right Heart Surgery. Circulation 94(9 Suppl): 1149-55, 1996 Nov 1
  13. Shekerdemian L.S., Bush A., Lincoln C., Shore D.F., Petros A.J. and Redington A.N. Cardiopulmonary interactions in Healthy Children and Children after simple Cardiac Surgery: the Effects of Positive and Negative Pressure Ventilation. Heart 1997 Dec; 78(6): 587-593
  14. Shekerdemian L.S., Bush A., Shore D.F., Lincoln C., and Redington A.N. Cardiopulmonary Interactions after Fontan Operations: Augmentation of Cardiac Output Using Negative Pressure Ventilation. Circulation 1997:96: 3934-3942
  15. Shekerdemian L.S., Schulze-Neick I., Redington A.N., Bush A. and Penny D.J. Negative Pressure Ventilation as Haemodynamic Rescue Following Surgery for Congenital Heart Disease. Intensive Care Med (2000) 26: 93 – 96
  16. Shekerdemian L.S., Bush A., Shore D.F., Lincoln C. and Redington A.N. Cardiorespiratory Responses to Negative Pressure Ventilation after Tetralogy of Fallot Repair: A Hemodynamic Tool for Patients with a Low-output State. Jounal of the American College of Cardiology Vol 33, Issue 2: 549 – 555
  17. Sideno B, Vaage J. Ventilation by External High-Frequency Oscillations Improves Cardiac Function after Coronary Artery Bypass Grafting. European Journal of Cardio-Thoracic Surgery 11 (1997) 248-257
  18. Shiga T., Takeda S., Nakanishi K., Takano T., Sakamoto A., and Ogawa R. Transesophageal Echocardiographic Evaluation During Negative – Pressure Ventilation using the Hayek Oscillator. Journal of Cardiothoracic and Vascular Anesthesia, Vol 12, No. 5 (October), 1998: 527 – 532
  19. Takeda S.,Nakanishi K. et al, External High Frequency Oscillation for Hypercapnia and Upper Abdominal Surgery, J Nippon Medical School 1997, 64 (5) 440-445
  20. Chendrasekhar A.,. Prabhakar G., Dulaney J., Barringer L.S. and Timberlake G.A., An Evaluation of the Effect of a Hayek Oscillator on Splachnic Perfusion in Acute Lung Injury. The Internet Journal of Emergency and Intensive Care Medicine 1997: Vol 1 N4 http://www.ispub.com/journals/IJEICM/Vol1N4/hayek.htm
  21. Scholz S.E., Knothe C., Thiel A. and Hempelmann G. Improved Oxygen Delivery by Positive Pressure Ventilation with Continuous Negative External Chest Pressure. The Lancet Saturday 3 May, 1997, Vol.349 No. 9061: 1295 – 1296
  22. Smithline HA, Rivers EP, Rady MY, Blake HC, Nowak RM. Biphasic Extrathoracic Pressure CPR. A Human Pilot Study. Chest 1994, 105: 842-846.
  23. Dilkes MG, Hill AC, McKelvie P, McNeil JM, Monks PS, Hollamby RG. The Hayek Oscillator: A New Method of Microlaryngeal surgery. Annals of Otology, Rhinology and Laryngology, 1993, 102: 455-458
  24. Dilkes MG, Broomhead C, McKelvie P, Monks PS. A New Method of Tubeless Anaesthesia for Upper Airway Laser Surgery. Lasers in Medical Science 1994, Vol 9. 55-58
  25. Monks PS, Broomhead CJ, Dilkes MG, McKelvie P. The Use of the Hayek Oscillator during Microlaryngeal Surgery. . Anaesthesia Oct. 1995, 50 (10): 865-869
  26. Broomhead CCJ, Dilkes MG, Monks PS. Use of the Hayek Oscillator in a case of Failed Fibreoptic Intubation. British Journal of Anaesthesia June1995, 74(6): 720-21
  27. Monks P.S., and Dilkes M.G. Anaesthesia for Endoscopic, Laser, Laryngeal and Airway Surgery using the Hayek Oscillator and Total Intravenous Anaesthesia. Minimally Invasive Therapy 1995: 4(Suppl 2): 27 – 30
  28. Monks P.S., Peck T.E. and Dilkes M.G. Anaesthesia for Daycare Lase Tonsillectomy using the Hayek Oscillator and Total Intravenous Anaesthesia. Min Invas Ther “&” Allied Technol 1996: 5: 203 – 206
  29. Sutcliffe N, Remington SAAM, Ramsay TM, Mason C. Severe Tracheal Stenosis and Operative Delivery. Anaesthesia Jan. 1995, 50 (1): 26 – 29
  30. Spitzer S, Fink G, Mittelman M. External High Frequency Oscillation in Patients with Chronic Obstructive Pulmonary Disease. Chest, 1993, 104: 1698 – 1701
  31. Walsh GR, Nevin M. External High Frequency Oscillation Ventilation. Intensive Care Britain 1994
  32. Takeda S., Nakanishi K., Takano T., Nejima J., Takayama M., Ishikawa G. and Ogawa R. The Combination of External High-Frequency Oscillation and Pressure Support Ventilation in Acute Respiratory Failure. Acta Anaesthesiol Scand. 1997;41:670-4
  33. Al-Saady NM, Fernando SSD, Petros AJ, Cummin ARC, Sidhu VS, Bennett ED. External High Frequency Oscillation in Normal Subjects and in Patients with Acute Respiratory Failure. Anaesthesia Dec.1995, 50 (12): 1031-1035
  34. Segawa J, Nakashima Y, Kuroiwa A, Rikimaru S, Kohara N, Shiba K. Experience in a Quadriplegic Patient with Alveolar Hypoventilation. Kokyu to Junkan, Respiration and Circulation March 1993, 41(3): 271-275
  35. Hardinge FM, Davies RJO, Stradling JR. Effects of Short Term High Frequency Negative Pressure Ventilation on Gas Exchange Using the Hayek Oscillator in Normal Subjects. Thorax 1995, 50: 44 – 49
  36. Dolmage T, James A. et al, Effects of External Chest Wall Oscillation on Gas Exchange in Healthy Subjects. Chest Vol 107 p433 – 439 Feb 1995
  37. Shigeoka J.W., New! Improved or Nothing New Under the Sun? Respiratory Care March 96 Vol 41 No.3
  38. Klonin H., Bowman B., Peters M., Raffeeq P., Durward A., Bohn D.J., Meliones J.N. and Cheifetz I.M. Negative Pressure Ventilation via Chest Cuirass to Decrease Ventilator-Associated Complications in Infants with Acute Respiratory Failure: A Case Series. Respiratory Care, May 2000, Vol 45 No. 5: 486 – 490
  39. Klonin H, Campbell C, Hawthorne J, Southall D.P., Samuels M.P, Negative extrathoracic pressure in infants with cystic fibrosis and respiratory failure. Paediatric Pulmonology 30: 260 – 264 (2000)
  40. Gaitini L, Krimerman S, Smorgik Y, Gruber A, Varzberger A, External HighVentilation for Weaning from Mechanical Ventilation. APICE congress, Trieste, November 23 – 26 1990, p137.
  41. Zobel G, Dacar D, Ridl S. Hemodynamic Effects of Different Modes of Mechanical Ventilation in Cardiac and Respiratory Failure: An Experimental Study. 13th Int. Sypmosium on Intensive Care and Emergency Medicine, Brussels 23 – 26 March, 1993 Clinical Intensive Care, 1993, Supplement to 4 (2): 82
  42. Campbell JM, Nevin M. Hayek Oscillator: Experience in Intensive Care. 13th Int. Sypmosium on Intensive Care and Emergency Medicine, Brussels 23 – 26 March, 1993 Clinical Intensive Care, 1993, Supplement to 4 (2): 92
  43. Bristow A. The Use of the Hayek Oscillator to Produce Postoperative Hyperventilation in the Neurosurgical Patient. Neuroanaesthetists Travelling Club of Great Britain “&” Ireland, April 3rd 1993
  44. Bennett MR, Blair KE, Fiehler PC, Kline LR. Chest Wall Oscillation in Acute Resp Failure Utilizing the Hayek Oscillator. Am Rev Resp Dis, 1993, Supplement to 147 (4): A983
  45. Besharat F, Soo Hoo GW, Ellison MJ, Zhang C, Williams AJ. Effects of External Chest Wall Oscillation in Stable COPD Patients, Southern California Pulmonary Research Conference, 17th Annual Session, January 21 – 23 1994
  46. Soo Hoo GW, Ellison MJ, Zhang C, Williams AJ, Belman MJ. Effects of External Chest Wall Oscillation in Stable COPD Patients, Resp and Crit Care Med, April, 1994, 149 (4) : A637
  47. O’Donnell CJ. Respiratory Support Using the Hayek Oscillator in a Spinal Injury Patient, UK Intensive Care Soc of UK and Ireland, April 1994
  48. Kampmann B, Habibi P, External Negative Pressure Ventilation Using the Hayek Oscillator – Experiences and Indications for Use. European Paediatric Intensive Care Meeting, Nice, June 2-5, 1994.
  49. Nava S., Bagliani S., Zocchi L. and Scabini M. Cllnical Evaluation of External High Frequency Oscillation (EHFO) vs Postural Drainage and Chest Percussion (PD+P) in Enhancing Expectoration. Resp and Crit Care Med,April 1997, Vol 155 No. 4 : A
  50. D. Burns, W Johnson, High Frequency Oscillation as Adjuvant Pneumonia Therapy in severe Head Injury. American Association of Neurological Surgeons Aug 17, 93 18:10
  51. Dolmage T., Eisenberg H, Davis L.L, Goldstein R S, Chest Wall Oscillation at 1 Hz Reduces Spontaneous Ventilation in Healthy Subjects During Sleep. Chest Vol. 110 Number 1, July 1996
  52. Boix Ruiz JH. A Comparative Study of the Effects on the Left Ventricular Function of 2 Methods of Noninvasive Ventilation: NIPPV and EHFO-NB Rev Clin ESP, March 1996; 196 (3): 162-163
  53. T. Scherer, J. Barandun, E. Martinez, A. Wanner, E.M.Rubin Effect of High Frequency Oral Airway and Chest Wall Oscillation and Conventional Chest Physical Therapy on Expectoration in Patients With Stable Cystic Fibrosis. Chest, Vol. 113, Number 4, April 1998
  54. S. Takeda, K. Nakanishi, T. Takano, G. Ishikawa, R. Ogawa Effect of External High-Frequency Oscillation on Severe Cardiogenic Pulmonary Edema. J Anesth (1997) 11:83-87/ MONITOR WORLD CD-ROM 2000 Journal of Anesthesia S.E. Scholtz, et al – Combination of External Chest Wall Oscillation with Continuous Positive Airway Pressure – British Journal of Anaesthesia; 87 (3): 441-6, September 2001
  55. James B. Fink and Michael J Mahlmeister, High Frequency Oscillation of the Airway and Chest Wall – Respiratory Care July 2002 Vol 47 No.7
  56. S.Heili Frades, R. Cabarcos Salas, C. Aguado Aparicio, M.A. Bodoque Diaz, M. Martinez Diaz, S. Lopez Martin, J. Gomez Seco, O. Ramon Sabillon, I Fernandez Ormaechea and G. Peces-Barba. Eficacia del oscilador Hayek en el tratamiento de pacientes con bronquiectasias. Rev Patol Respir 2002;5(2): 55 – 58
  57. Schonfeld T, Ben-Abraham R Is external high frequency oscillation in the treatment of organophosphate poisoning in cats a useful and easily applied method for prehospital ventilatory support? Med Sci Monit, Jun 2003, 9(6) pBR207 – 10
  58. Sven Plein et al, Cardiac MR Imaging with External Respirator: Synchronizing Cardiac and Respiratory Motion – Feasibility Study1 Radiology June 2003; 227: 877 – 882
  59. P Protects, Paditz E, Heubner G, Keymer S Nichtinvasive nachtliche externe Unterdruckbeatmung im 2. Lebensjahr bei spinaler Muskelatrophie Typ I Saxonian-Thuringian Society for Child and Youth Medicine 2003 – http://www.stgkjm.de/abstracts/V22.htm
  60. S. Chari, J. King, P.B.Rajesh, K. Stuart-Smith Case Report: Resolution of left lower lobe collapse post-oesophagectomy using the United Hayek RTX Respirator, a novel non-invasive respiratory support system. The Journal of Cardiothoracic and Vascular Anaesthesia Vol 18, No 4 (August), 2004: pp 482 – 485
  61. Ron Ben-Abraham , Ilan Gur , Ephraim Bar – Yishay , Guy Lin , Amir Blumenfeld, Boaz Kalmovich and Avi A. Weinbroum – Application of a cuirass and institution of biphasic extra-thoracic ventilation by gear-protected physicians – Journal of Critical Care, Volume 19, Issue 1, March 2004, Pages 36 – 41
  62. D.M. Linton Cuirass Ventilation: A Review and Update Critical Care and Resuscitation 2005; 7: 113 – 122
  63. D. Shoseyov, D.Linton, M.R. Kramer, E.Kerem Non invasive negative biphasic cuirass ventilator as a bridge to Lung transplant in Cystic Fibrosis Journal of Cystic Fibrosis 4 (2005) S59 – S73
  64. A Al-balkhi, H Klonin, K Marinaki, D P Southall, D A Thomas, P Jones, M P Samuels Review of treatment of bronchiolitis related apnoea in two centres Arch Dis Child 2005; 90: 288-291 – I Gur, E Bar Yishay, R Ben-Abraham – Biphasic extrathoracic cuirass ventilation for resuscitation American Journal of Emergency Medicine (2005) 23, 488-491
  65. D.M. Linton Cuirass Ventilation: A Review and Update Critical Care and Resuscitation 2005; 7: 113-122
  66. D. Shoseyov, D.Linton, M.R. Kramer, E.Kerem Non invasive negative biphasic cuirass ventilator as a bridge to Lung transplant in Cystic Fibrosis – Journal of Cystic Fibrosis 4 (2005) S59-S73
  67. G. Fernandes, E. Araujo, E. Mateus, I. Gomes Blood Gases and Functional Changes after Treatment with Hayek Oscillator secretion Mode Eur Respir J 2005; 26: Suppl. 49, 529s
  68. A Al-Balkhi, H Klonin, K Marinaki, D P Southall, D A Thomas, P Jones, M P Samuels Review of treatment of bronchiolitis related apnoea in two centres Arch Dis Child 2005; 90: 288 – 291
  69. S. Sviri, D.M. Linton, P.V. Van Heerden Non-invasive Mechanical Ventilation Enhances Patient Autonomy in Decision Making Regarding Chronic Ventilation Critical Care and Resuscitation, 2005; 7: 116 – 118
  70. I Gur, E Bar Yishay, R Ben-Abraham Biphasic extrathoracic cuirass ventilation for resuscitation American Journal of Emergency Medicine (2005) 23, 488 – 491 – Tsukamoto K, Minimiya R, Nishihara T, Kawamata M, Kotani T – An example of the critical muscle helpless symptom Respiratory Assisted by Biphasic Cuirass Ventilation in Myasthenia Gravis child Japanese Society of Anesthesiologists 2006 June P2 – 50 – 06
  71. Toyoshima M, Maeoka Y, Kawahara H, Maegaki Y, Ohno K Pulmonary atelectasis in patients with neurological or muscular disease; gravity-related lung compression by the heart and intra-abdominal organs on persistant supine position – No To Hattatsu 2006 Nov;38(6):419 – 424
  72. D M Linton, S Sviri – Conservative management of flail chest after cardiopulmonary resuscitation by continuous negative extrathoracic pressure Critical Care and Resuscitation, Volume 8 Number 4, December 2006, 339 – 340
  73. N Shime, C Toida, T Itoi, S Hashimoto – Continuous negative extrathoracic pressure in Children after congenital heart surgery. Critical Care and Resuscitation, Volume 8 Number 4, December 2006, 297 – 301
  74. Rathbone, Phillip; Stuart-Smith, Karen. Use of the United Hayek RTX Respirator, A Biphasic Non-Invasive Cuirass Ventilator, in Neurological Disease Complicated by Acute Respiratory Failure. Critical Care Medicine: Volume 34(12) December 2006 p A170

And Many More!

While this is a sampling of the most relevant data on BCV, we have several hundred studies not listed here. If you are looking for more specific information, please reach out to us and we will find what you are looking for!